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Knee · Soft Tissue

Plica Syndrome

A plica is a fold of synovial tissue inside the knee. In most people it causes no problems, but in some it becomes inflamed and thickened, producing pain and clicking that can mimic other knee pathology.

Area Knee
Treatment Conservative · Surgical

What is plica syndrome?

A plica is a remnant of fetal connective tissue inside the knee joint. Most people have one or more plicae and never know it, they cause no problems. In some patients, however, a plica becomes thickened, inflamed and irritated, often after a minor injury or repeated overuse. When this happens, the plica can rub against the cartilage and produce a recognisable pattern of pain and clicking known as plica syndrome.

What causes plica syndrome?

  • direct trauma to the knee
  • repetitive overuse, particularly cycling, running, prolonged squatting
  • post-surgical inflammation
  • any cause of chronic synovitis

The medial plica is by far the most commonly symptomatic.

What are the symptoms?

  • pain on the inner side of the knee, around the medial border of the patella
  • clicking or snapping with movement, often reproducible at a specific angle of flexion
  • pain with prolonged sitting ("theatre sign")
  • pain with stairs and squatting
  • occasional swelling

Plica syndrome is often confused with meniscus tears or patellofemoral pain, careful clinical examination is essential.

How is the diagnosis made?

  • detailed history and clinical examination, including the medial plica test
  • exclusion of other diagnoses (meniscus tear, MCL injury, patellofemoral pain)
  • MRI, can sometimes visualise a thickened plica, but is more useful for excluding other pathology
  • the diagnosis is often confirmed at arthroscopy

What is the conservative treatment?

The vast majority of patients improve with conservative treatment:

  • activity modification, particularly avoiding prolonged squatting and repetitive flexion
  • anti-inflammatory medication
  • structured physiotherapy with quadriceps strengthening and stretching
  • ultrasound-guided injection in selected resistant cases

It is worth being clear that a properly conducted conservative programme of at least 3 months should be tried before considering surgery.

How is surgical treatment performed?

Surgery is performed arthroscopically. During the procedure I excise the symptomatic plica, removing the inflamed, thickened tissue while preserving the surrounding healthy joint. The procedure is minimally invasive and gives excellent results in well-selected patients. I apply modern arthroscopic techniques aiming for stable repair and optimal functional recovery.

What should the patient expect after surgery?

  • day-case admission
  • weight-bearing as tolerated from the first day
  • early structured physiotherapy
  • return to running typically at 4–6 weeks
  • return to full sport at 6–8 weeks
Treatments offered

Treating plica syndrome.

Most cases respond to conservative treatment. Surgery is reserved for the small minority that fail to improve.

Treatment · Non-surgical
Activity Modification & Physiotherapy

First-line treatment. Reduced loading, anti-inflammatory medication, targeted physiotherapy. Most patients improve.

Service · Arthroscopic
Arthroscopic Plica Excision

For persistent symptoms after a thorough conservative trial. The thickened plica is removed arthroscopically.

SE

Medically reviewed by Dr Spyros Economou

Orthopaedic Surgeon – Traumatologist · German-trained · Limassol

Persistent clicking or pain in the knee?

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